产品货号：
Z32054
中文名称：
Claudin 4/CLDN4抗体
英文名称：
Anti-Claudin 4/CLDN4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Claudin 4/CLDN4 Antibody |
| 指标别名 | claudin 4;Claudin 4-specific;CLDN4;CPE R;CPE receptor;CPER;CPETR;CPETR1;hCPE R;WBSCR8 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | CLDN4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Claudin 4 Plays a major role in tight junction-specific obliteration of the intercellular space. |
| 实际分子量 | 18KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The claudin superfamily consists of many structurally related proteins in humans.These proteins are important structural and functional components of tight junctions in paracellular transport.Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues.Three classes of proteins are known to localize to tight junctions,including the claudins,Occludin and junction adhesion molecule.Claudins,which consist of four transmembrane domains and two extracellular loops make up tight junction strands.Claudin expression is highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.Claudin-4 is not expressed in rat liver,whereas in pancreas,claudin-4 is localized to junctions of the duct epithelia and junctions of acinar cells.In the rat gut,claudin-4 displays highly restricted expression to colonic surface cells.The human claudin-4 gene maps to chromosome 7q11.23. |
| Uniprot ID | O14493 |
| 推荐稀释比 | Western blot (WB) 1:400～800 Immunohistochemistry in paraffin section (IHC) 1:20～100 |
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